Description

3-(4-Methylphenyl)-4'-Trifluoromethylpropiophenone is a high-purity, specialized organic intermediate featuring a trifluoromethyl group, a key structural motif known to enhance the biological activity and metabolic stability of target molecules. This compound is critical for research and development chemists seeking to synthesize novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily utilized by the pharmaceutical, agrochemical, and advanced materials industries for the construction of complex molecules where the introduction of fluorine is required.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group improves lipophilicity and biological efficacy.
• Material Science Research: Serves as a precursor for developing specialty polymers and liquid crystals with unique optical and electronic properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies in fluorination chemistry and cross-coupling reactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in producing bespoke fine chemicals for client projects.

Basic Information

Product Name	3-(4-Methylphenyl)-4'-Trifluoromethylpropiophenone
CAS No.	898769-04-5
Molecular Formula	C17H15F3O
Molecular Weight	292.30 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-3-(4-methylphenyl)propan-1-one; 3-(p-Tolyl)-1-[4-(trifluoromethyl)phenyl]propan-1-one; 4'-Methyl-3-(trifluoromethyl)propiophenone derivative; Propiophenone, 3-(4-methylphenyl)-4'-(trifluoromethyl)-; p-Methyl-β-phenylpropiophenone, 4'-trifluoromethyl-
EINECS	Contact for details

Quality Control

Our 3-(4-Methylphenyl)-4'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade starting materials and research standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.