Description

3-(4-Methylphenyl)-3'-Trifluoromethylpropiophenone is a specialized organic intermediate featuring a propiophenone core substituted with methylphenyl and trifluoromethyl groups. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical molecules, where the trifluoromethyl group is a key pharmacophore enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl moiety.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials and organic light-emitting diodes (OLEDs) due to its aromatic and fluorinated structure.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D laboratories.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various technological applications.

Basic Information

Product Name	3-(4-Methylphenyl)-3'-Trifluoromethylpropiophenone
CAS No.	898769-01-2
Molecular Formula	C17H15F3O
Molecular Weight	292.30 g/mol
Synonyms	1-[3-(Trifluoromethyl)phenyl]-3-(4-methylphenyl)-1-propanone; 3-(4-Methylphenyl)-1-[3-(trifluoromethyl)phenyl]propan-1-one; 3-(p-Tolyl)-3'-(trifluoromethyl)propiophenone; 3-(4-Methylphenyl)-3'-(trifluoromethyl)propiophenone; 898769-01-2; Propiophenone, 3-(4-methylphenyl)-3'-(trifluoromethyl)-; 1-Propanone, 1-[3-(trifluoromethyl)phenyl]-3-(4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 3-(4-Methylphenyl)-3'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.