Description

2'-Fluoro-3-(4-Methylphenyl)Propiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. Pharmaceutical research organizations and fine chemical manufacturers need this precise intermediate for constructing complex molecular architectures, particularly in medicinal chemistry programs targeting CNS and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, especially those requiring a fluorinated biaryl motif.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides where the fluorine atom enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials, contributing to improved charge transport and emission properties.
• Advanced Polymer Chemistry: Incorporated as a monomer or cross-linking agent to create specialty polymers with unique thermal and optical characteristics.
• Chemical Biology Probes: Utilized in the synthesis of fluorinated probes and tags for studying biological mechanisms and protein interactions.
• Catalyst Ligand Synthesis: Acts as a starting material for constructing sophisticated ligand systems in asymmetric catalysis.

Basic Information

Product Name	2'-Fluoro-3-(4-Methylphenyl)Propiophenone
CAS No.	898768-97-3
Molecular Formula	C16H15FO
Molecular Weight	242.29 g/mol
Synonyms	1-(2-Fluorophenyl)-3-(p-tolyl)propan-1-one; 3-(4-Methylphenyl)-1-(2-fluorophenyl)propan-1-one; 2'-Fluoro-3-p-tolylpropiophenone; β-(4-Methylphenyl)-2'-fluoropropiophenone; 898768-97-3; FMPP (abbreviation); Propiophenone, 2'-fluoro-3-(4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 2'-Fluoro-3-(4-Methylphenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for demanding research and scale-up applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.