Description

4'-Chloro-3'-Fluoro-3-(4-Methylphenyl)Propiophenone is a high-purity fluorinated and chlorinated aromatic ketone, serving as a critical advanced intermediate in modern organic synthesis. Its precise molecular architecture makes it an essential building block for the development of novel, high-value compounds, particularly in the pharmaceutical sector. This product is primarily targeted at research institutions and industrial manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials, where structural complexity and purity are paramount.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging its halogenated structure for enhanced biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a foundational component in the synthesis of fluorinated organic molecules for electronic display and lighting technologies.
• Organic Ligand & Catalyst Development: Employed in academic and industrial research to create complex ligands for catalytic systems and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical synthesis projects requiring specific halogenated intermediates.

Basic Information

Product Name	4'-Chloro-3'-Fluoro-3-(4-Methylphenyl)Propiophenone
CAS No.	898768-91-7
Molecular Formula	C16H14ClFO
Molecular Weight	276.73 g/mol
Synonyms	1-(4-Chloro-3-fluorophenyl)-3-(p-tolyl)propan-1-one; 3-(4-Methylphenyl)-1-(4-chloro-3-fluorophenyl)propan-1-one; 4'-Chloro-3'-fluoro-3-(p-tolyl)propiophenone; 898768-91-7; Propiophenone, 4'-chloro-3'-fluoro-3-(4-methylphenyl)-; 1-(4-Chloro-3-fluorophenyl)-3-(4-methylphenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 4'-Chloro-3'-Fluoro-3-(4-Methylphenyl)Propiophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical and advanced material research. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.