Description

4'-Bromo-3'-Fluoro-3-(4-Methylphenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its halogenated phenylpropiophenone core structure.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals, leveraging its aromatic and ketone functionalities.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and other catalytic transformations to create novel chemical entities for screening libraries.

Basic Information

Product Name	4'-Bromo-3'-Fluoro-3-(4-Methylphenyl)Propiophenone
CAS No.	898768-89-3
Molecular Formula	C16H14BrFO
Molecular Weight	321.19 g/mol
Synonyms	1-(4-Bromo-3-fluorophenyl)-3-(p-tolyl)propan-1-one; 3-(4-Methylphenyl)-1-(4-bromo-3-fluorophenyl)propan-1-one; 4'-Bromo-3'-fluoro-3-(p-tolyl)propiophenone; 1-Propanone, 1-(4-bromo-3-fluorophenyl)-3-(4-methylphenyl)-; p-Methyl-β-(4-bromo-3-fluorobenzoyl)ethylbenzene
EINECS	Contact for details

Quality Control

Our 4'-Bromo-3'-Fluoro-3-(4-Methylphenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and current industry standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.