Description

3-(4-Fluorophenyl)-3',4',5'-Trifluoropropiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its precise molecular architecture, featuring multiple fluorine substituents, is engineered to impart desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. This compound is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in kinase inhibitor and CNS-active molecule libraries.
• Agrochemical Synthesis: Serves as a versatile building block for creating novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Liquid Crystal Materials: Used in the synthesis of fluorinated components for advanced liquid crystal displays (LCDs) due to its influence on dielectric anisotropy and viscosity.
• Organic Electronic Materials: Acts as a precursor in the development of materials for organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Advanced Polymer Chemistry: Incorporated as a monomer or cross-linking agent to create specialty polymers with unique thermal and chemical resistance.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new fluorination chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	3-(4-Fluorophenyl)-3',4',5'-Trifluoropropiophenone
CAS No.	898768-82-6
Molecular Formula	C15H8F4O
Molecular Weight	280.22 g/mol
Synonyms	1-[3,4,5-Trifluorophenyl]-3-(4-fluorophenyl)-1-propanone; 3',4',5'-Trifluoro-3-(4-fluorophenyl)propiophenone; 3-(4-Fluorophenyl)-1-(3,4,5-trifluorophenyl)propan-1-one; 4-Fluoro-β-(3,4,5-trifluorobenzoyl)ethylbenzene; Propiophenone, 3-(4-fluorophenyl)-3',4',5'-trifluoro-; 898768-82-6; 3-(4-Fluorophenyl)-3',4',5'-trifluoropropiophenon
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-3',4',5'-Trifluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.