Description

3'-Fluoro-3-(4-Methylphenyl)Propiophenone is a high-value fluorinated aromatic ketone building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by research chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, including potential kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Research: Used in the development of novel herbicides and pesticides where the fluorine atom and aromatic ketone moiety enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated mesogens and electron-transport materials in display and lighting technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, carbonyl chemistry, and as a scaffold for constructing more complex polycyclic aromatic structures in academic and industrial R&D.
• Fluorine Chemistry Studies: Used as a model compound for studying the effects of fluorine substitution on the reactivity and physical properties of aromatic ketones.

Basic Information

Product Name	3'-Fluoro-3-(4-Methylphenyl)Propiophenone
CAS No.	898768-75-7
Molecular Formula	C₁₆H₁₅FO
Molecular Weight	242.29 g/mol
Synonyms	1-(3-Fluorophenyl)-3-(p-tolyl)propan-1-one; 3-Fluoro-3'-(4-methylphenyl)propiophenone; 3'-Fluoro-3-(4-methylphenyl)propiophenone; 3-(4-Methylphenyl)-1-(3-fluorophenyl)-1-propanone; 1-Propanone, 1-(3-fluorophenyl)-3-(4-methylphenyl)-; 3-Fluoro-3-(4-methylphenyl)propiophenone
EINECS	Contact for details

Quality Control

Our 3'-Fluoro-3-(4-Methylphenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.