Description

4'-Bromo-2'-Fluoro-3-(4-Fluorophenyl)Propiophenone is a high-purity fluorinated and brominated aromatic ketone, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its unique halogenated structure makes it essential for constructing complex molecules, particularly in medicinal chemistry where precise halogen substitution is required for bioactivity and metabolic stability. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Stille) and other transformations in complex organic molecule construction.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	4'-Bromo-2'-Fluoro-3-(4-Fluorophenyl)Propiophenone
CAS No.	898768-60-0
Molecular Formula	C15H11BrF2O
Molecular Weight	325.15 g/mol
Synonyms	1-(4-Bromo-2-fluorophenyl)-3-(4-fluorophenyl)propan-1-one; 3-(4-Fluorophenyl)-1-(4-bromo-2-fluorophenyl)propan-1-one; 4'-Bromo-2'-fluoro-3-(4-fluorophenyl)propiophenone; 898768-60-0; 4-Bromo-2-fluoro-3-(4-fluorophenyl)propiophenone; Propiophenone, 4'-bromo-2'-fluoro-3-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 4'-Bromo-2'-Fluoro-3-(4-Fluorophenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.