Description

2'-Chloro-3-(4-Fluorophenyl)Propiophenone is a high-value, fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory activity.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and stability.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, or organic electronic materials that require specific fluorinated aromatic components.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies in cross-coupling reactions, carbonyl chemistry, and fluorinated compound manipulation.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses producing bespoke fine chemicals for client-specific projects.

Basic Information

Product Name	2'-Chloro-3-(4-Fluorophenyl)Propiophenone
CAS No.	898768-52-0
Molecular Formula	C15H12ClFO
Molecular Weight	262.71 g/mol
Synonyms	1-(2-Chlorophenyl)-3-(4-fluorophenyl)propan-1-one; 3-(4-Fluorophenyl)-1-(2-chlorophenyl)-1-propanone; 2'-Chloro-3-(p-fluorophenyl)propiophenone; Propiophenone, 2'-chloro-3-(4-fluorophenyl)-; 898768-52-0; 1-Propanone, 1-(2-chlorophenyl)-3-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2'-Chloro-3-(4-Fluorophenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP or research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.