Description

4'-Bromo-3'-Fluoro-3-(4-Fluorophenyl)Propiophenone is a high-purity, multi-functional fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its precise molecular architecture, featuring strategically placed bromine and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a sophisticated monomer for creating advanced functional materials used in display technologies and organic electronics.
• Cross-Coupling Reactions: The bromine atom provides an excellent handle for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl structures.
• Chemical Research & Development: An essential tool for academic and industrial R&D labs exploring new synthetic methodologies and fluorine chemistry.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific fluorinated motifs.

Basic Information

Product Name	4'-Bromo-3'-Fluoro-3-(4-Fluorophenyl)Propiophenone
CAS No.	898768-43-9
Molecular Formula	C15H11BrF2O
Molecular Weight	325.15 g/mol
Synonyms	1-(4-Bromo-3-fluorophenyl)-3-(4-fluorophenyl)propan-1-one; 3-(4-Fluorophenyl)-1-(4-bromo-3-fluorophenyl)propan-1-one; 4'-Bromo-3'-fluoro-3-(4-fluorophenyl)propiophenone; 898768-43-9; Propiophenone, 4'-bromo-3'-fluoro-3-(4-fluorophenyl)-; 1-(4-Bromo-3-fluorophenyl)-3-(4-fluorophenyl)-1-propanone
EINECS	Contact for details

Quality Control

Every batch of 4'-Bromo-3'-Fluoro-3-(4-Fluorophenyl)Propiophenone is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), identity confirmation, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.