Description

3',4'-Dimethyl-3-(4-Fluorophenyl)Propiophenone is a high-purity, fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research chemists and process development teams in pharmaceutical, agrochemical, and advanced material industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand & Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of monomers for specialty polymers and advanced organic electronic materials.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
• Academic & Contract Research: A valuable reagent for exploratory organic chemistry and medicinal chemistry programs in academic and CRO settings.

Basic Information

Product Name	3',4'-Dimethyl-3-(4-Fluorophenyl)Propiophenone
CAS No.	898768-37-1
Molecular Formula	C17H17FO
Molecular Weight	256.32 g/mol
Synonyms	1-(3,4-Dimethylphenyl)-3-(4-fluorophenyl)propan-1-one; 3-(4-Fluorophenyl)-1-(3,4-dimethylphenyl)propan-1-one; 3',4'-Dimethyl-3-(p-fluorophenyl)propiophenone; 4-Fluoro-β-(3,4-dimethylbenzoyl)ethylbenzene; Propiophenone, 3',4'-dimethyl-3-(4-fluorophenyl)-; 898768-37-1; 3-(4-Fluorophenyl)-1-(3,4-dimethylphenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 3',4'-Dimethyl-3-(4-Fluorophenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.