Description

3-(3-Methylphenyl)-3',4',5'-Trifluoropropiophenone is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its value lies in its unique trifluoromethylphenyl and propiophenone structure, which serves as a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and specialty materials. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and advanced material science industries seeking to incorporate fluorinated motifs for enhanced bioactivity and material properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where the fluorinated aromatic core improves efficacy and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated compounds used in electronic display technologies and organic light-emitting diodes.
• Polymer Modification: Incorporated into specialty polymer chains to alter thermal stability, solubility, and chemical resistance.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring novel fluorination chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	3-(3-Methylphenyl)-3',4',5'-Trifluoropropiophenone
CAS No.	898768-24-6
Molecular Formula	C16H13F3O
Molecular Weight	278.27 g/mol
Synonyms	1-(3,4,5-Trifluorophenyl)-3-(m-tolyl)propan-1-one; 3',4',5'-Trifluoro-3-methylpropiophenone; m-Tolyl 3,4,5-trifluorophenyl ketone; 3-Methylphenyl 3,4,5-trifluorophenyl ketone; 898768-24-6; Propiophenone, 3-(3-methylphenyl)-3',4',5'-trifluoro-; 3-(3-Methylphenyl)-3,4,5-trifluoropropiophenone
EINECS	Contact for details

Quality Control

Our 3-(3-Methylphenyl)-3',4',5'-Trifluoropropiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.