Description

3-(4-Fluorophenyl)-2'-Methylpropiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical sector. It is primarily sought after by research and development chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and inflammatory conditions.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorophenyl moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers due to its aromatic and fluorinated structure.
• Chemical Research & Development: A versatile synthon for academic and industrial research exploring new carbon-carbon bond formation reactions and heterocyclic chemistry.

Basic Information

Product Name	3-(4-Fluorophenyl)-2'-Methylpropiophenone
CAS No.	898767-85-6
Molecular Formula	C16H15FO
Molecular Weight	242.29 g/mol
Synonyms	1-(4-Fluorophenyl)-3-phenyl-2-butanone; 2'-Methyl-3-(4-fluorophenyl)propiophenone; 3-(4-Fluorophenyl)-2-methylpropiophenone; 3-(p-Fluorophenyl)-2'-methylpropiophenone; Propiophenone, 3-(4-fluorophenyl)-2'-methyl-; α-Methyl-4-fluorobenzylacetophenone
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-2'-Methylpropiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.