Description

3-(3-Fluorophenyl)-3',4',5'-Trifluoropropiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its precise molecular architecture, featuring multiple fluorine substituents, makes it a critical intermediate for developing novel compounds with tailored properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity, stability, and environmental profile.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, contributing to improved performance and durability.
• Polymer Modification: Employed to introduce fluorinated phenyl groups into polymer backbones, enhancing material properties like chemical resistance, thermal stability, and surface characteristics.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, carbonyl chemistry, and as a scaffold for constructing complex, multi-fluorinated aromatic systems in academic and industrial R&D.

Basic Information

Product Name	3-(3-Fluorophenyl)-3',4',5'-Trifluoropropiophenone
CAS No.	898767-73-2
Molecular Formula	C15H8F4O
Molecular Weight	280.22 g/mol
Synonyms	1-[3,4,5-Trifluorophenyl]-3-(3-fluorophenyl)-1-propanone; 3',4',5'-Trifluoro-3-fluoropropiophenone; 3-(3-Fluorophenyl)-1-(3,4,5-trifluorophenyl)propan-1-one; Propiophenone, 3-(3-fluorophenyl)-3',4',5'-trifluoro-; 898767-73-2; 3-Fluoro-3',4',5'-trifluoropropiophenone
EINECS	Contact for details

Quality Control

Our production of 3-(3-Fluorophenyl)-3',4',5'-Trifluoropropiophenone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP and ISO standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.