Description

2',4'-Dichloro-3-(3-Fluorophenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its defined molecular architecture enables precise chemical transformations. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and specialty chemicals. Consistent quality and reliable supply of this intermediate are paramount for ensuring the integrity of downstream synthesis processes.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, leveraging its halogenated phenylpropiophenone core.
• Organic Chemistry Research: Employed in academic and industrial R&D for studying cross-coupling reactions and exploring new synthetic methodologies.
• Fine Chemical Production: Acts as a specialized building block for manufacturing complex, high-value organic compounds used in various industrial applications.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	2',4'-Dichloro-3-(3-Fluorophenyl)Propiophenone
CAS No.	898767-59-4
Molecular Formula	C15H11Cl2FO
Molecular Weight	297.15 g/mol
Synonyms	1-(2,4-Dichlorophenyl)-3-(3-fluorophenyl)propan-1-one; 3-(3-Fluorophenyl)-1-(2,4-dichlorophenyl)propan-1-one; 2,4-Dichloro-3'-(fluorophenyl)propiophenone; 898767-59-4; Propiophenone, 2',4'-dichloro-3-(3-fluorophenyl)-; 1-Propanone, 1-(2,4-dichlorophenyl)-3-(3-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2',4'-Dichloro-3-(3-Fluorophenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.