Description

4'-Chloro-2'-Fluoro-3-(3-Fluorophenyl)Propiophenone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its precise molecular architecture, featuring strategically placed halogen atoms, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is primarily required by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

This specialized intermediate serves as a key precursor in several high-value synthetic pathways.

• Pharmaceutical Intermediate: Core building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, where the fluorinated phenyl group enhances biological activity and stability.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and specialty polymers.
• Chemical Research & Development: A valuable reagent for method development and exploring new fluorination reactions and cross-coupling methodologies in academic and industrial labs.

Basic Information

Item	Detail
Product Name	4'-Chloro-2'-Fluoro-3-(3-Fluorophenyl)Propiophenone
CAS No.	898767-55-0
Molecular Formula	C15H11ClF2O
Molecular Weight	280.70 g/mol
Synonyms	1-(4-Chloro-2-fluorophenyl)-3-(3-fluorophenyl)propan-1-one; 3-(3-Fluorophenyl)-1-(4-chloro-2-fluorophenyl)propan-1-one; 4'-Chloro-2'-fluoro-3-(3-fluorophenyl)propiophenone; 898767-55-0; Propiophenone, 4'-chloro-2'-fluoro-3-(3-fluorophenyl)-
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production follows cGMP principles where applicable, and every batch is analyzed using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.