Description

2'-Chloro-4'-Fluoro-3-(3-Fluorophenyl)Propiophenone is a high-purity fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its precise molecular architecture makes it a critical building block for the development of complex, biologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the creation of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its fluorinated structure for enhanced activity and stability.
• Material Science: Serves as a monomer or building block for synthesizing specialty polymers and liquid crystals with unique optical or electronic properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for constructing complex molecular frameworks and studying novel reaction pathways.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	2'-Chloro-4'-Fluoro-3-(3-Fluorophenyl)Propiophenone
CAS No.	898767-50-5
Molecular Formula	C15H11ClF2O
Molecular Weight	280.70 g/mol
Synonyms	1-(2-Chloro-4-fluorophenyl)-3-(3-fluorophenyl)propan-1-one; 3-(3-Fluorophenyl)-1-(2-chloro-4-fluorophenyl)propan-1-one; 2-Chloro-4-fluoro-3'-(3-fluorophenyl)propiophenone; 898767-50-5; Propiophenone, 2'-chloro-4'-fluoro-3-(3-fluorophenyl)-; 1-Propanone, 1-(2-chloro-4-fluorophenyl)-3-(3-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our production of 2'-Chloro-4'-Fluoro-3-(3-Fluorophenyl)Propiophenone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development and commercial projects requiring compliance with ICH guidelines and cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.