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4'-Bromo-2'-Fluoro-3-(3-Fluorophenyl)Propiophenone CAS NO 898767-47-0


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CAS No.:898767-47-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4'-Bromo-2'-Fluoro-3-(3-Fluorophenyl)Propiophenone is a high-purity fluorinated and brominated aromatic ketone, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique halogenated structure makes it an indispensable building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
  • Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine and bromine atoms contribute to biological activity and metabolic stability.
  • Material Science: Serves as a monomer or building block for creating specialty polymers and liquid crystals with specific optical or electronic properties.
  • Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions to introduce complex aryl groups.
  • Chemical Research & Development: A valuable reagent for medicinal chemists and process chemists exploring new synthetic pathways and optimizing lead compounds.

Basic Information

Product Name 4'-Bromo-2'-Fluoro-3-(3-Fluorophenyl)Propiophenone
CAS No. 898767-47-0
Molecular Formula C15H11BrF2O
Molecular Weight 325.15 g/mol
Synonyms 1-(4-Bromo-2-fluorophenyl)-3-(3-fluorophenyl)propan-1-one; 3-(3-Fluorophenyl)-1-(4-bromo-2-fluorophenyl)propan-1-one; 4'-Bromo-2'-fluoro-3-(3-fluorophenyl)propiophenone; 898767-47-0; Propiophenone, 4'-bromo-2'-fluoro-3-(3-fluorophenyl)-; 1-Propanone, 1-(4-bromo-2-fluorophenyl)-3-(3-fluorophenyl)-
EINECS Contact for details

Quality Control

Every batch of 4'-Bromo-2'-Fluoro-3-(3-Fluorophenyl)Propiophenone is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee reliable and reproducible performance in your applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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