Description

3-(3-Fluorophenyl)-4'-Trifluoromethylpropiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular scaffold, which incorporates both phenyl and trifluoromethyl groups, making it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and liquid crystals with specific optical or electronic properties.
• Organic Synthesis Reagent: Employed in various name reactions, such as Friedel-Crafts acylation or Suzuki coupling, to introduce fluorinated aromatic segments into more complex structures.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	3-(3-Fluorophenyl)-4'-Trifluoromethylpropiophenone
CAS No.	898767-44-7
Molecular Formula	C16H12F4O
Molecular Weight	296.26 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-3-(3-fluorophenyl)-1-propanone; 3-(3-Fluorophenyl)-1-[4-(trifluoromethyl)phenyl]propan-1-one; 4'-Trifluoromethyl-3-(3-fluorophenyl)propiophenone; 3-Fluoro-3'-(trifluoromethyl)propiophenone; Propiophenone, 3-(3-fluorophenyl)-4'-(trifluoromethyl)-; 898767-44-7; FC-Ph-Ketone Intermediate
EINECS	Contact for details

Quality Control

Our 3-(3-Fluorophenyl)-4'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.