Description

3-(3-Fluorophenyl)-3'-Trifluoromethylpropiophenone is a high-value fluorinated aromatic ketone intermediate. This compound is critical for its role in synthesizing complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) with fluorinated motifs, potentially for CNS, anti-inflammatory, or antiviral applications.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides where the trifluoromethyl and fluorophenyl groups enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or intermediate for synthesizing specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Synthesis Reagent: Employed in organic synthesis for Friedel-Crafts acylation reactions and as a precursor for further functionalization to chalcones or heterocyclic compounds.
• Life Science Research: Utilized in academic and industrial R&D as a probe or scaffold for drug discovery and medicinal chemistry programs.

Basic Information

Item	Detail
Product Name	3-(3-Fluorophenyl)-3'-Trifluoromethylpropiophenone
CAS No.	898767-41-4
Molecular Formula	C16H10F4O
Molecular Weight	294.25 g/mol
Synonyms	1-[3-(3-Fluorophenyl)-3-oxopropyl]-3-(trifluoromethyl)benzene; 3'-Trifluoromethyl-3-(3-fluorophenyl)propiophenone; 3-(3-Fluorophenyl)-1-[3-(trifluoromethyl)phenyl]propan-1-one; 3-(3-Fluorophenyl)-3'-(trifluoromethyl)propiophenone; Propiophenone, 3-(3-fluorophenyl)-3'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-(3-Fluorophenyl)-3'-Trifluoromethylpropiophenone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.