Description

3-(3-Fluorophenyl)-2'-Trifluoromethylpropiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both phenyl and trifluoromethyl groups, makes it a valuable precursor for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Serves as a crucial building block for synthesizing advanced herbicides, fungicides, and insecticides, leveraging the stability imparted by fluorine atoms.
• Material Science Precursor: Used in the synthesis of specialty polymers, liquid crystals, and organic electronic materials where fluorinated aromatic units are required.
• Chemical Synthesis: Acts as a versatile intermediate in organic chemistry for Friedel-Crafts acylation, Grignard reactions, and reductive amination processes.
• R&D Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	3-(3-Fluorophenyl)-2'-Trifluoromethylpropiophenone
CAS No.	898767-38-9
Molecular Formula	C₁₆H₁₂F₄O
Molecular Weight	296.26 g/mol
Synonyms	1-[3-(3-Fluorophenyl)propyl]-2-(trifluoromethyl)benzene; 3-(3-Fluorophenyl)-1-[2-(trifluoromethyl)phenyl]propan-1-one; 2'-Trifluoromethyl-3-(3-fluorophenyl)propiophenone; 3-(3-Fluorophenyl)-2'-(trifluoromethyl)propiophenone; Propiophenone, 3-(3-fluorophenyl)-2'-(trifluoromethyl)-; 898767-38-9; 3-(3-Fluorophenyl)-2'-trifluoromethyl propiophenone
EINECS	Contact for details

Quality Control

Our 3-(3-Fluorophenyl)-2'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for research and development chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.