Description

5-(2-Fluorophenyl)-5-Oxovaleronitrile is a high-purity, specialized organic intermediate featuring a fluorinated aromatic ketone moiety linked to a nitrile-terminated alkyl chain. This unique molecular architecture makes it a valuable synthon for constructing complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a starting material for synthesizing specialized polymers, liquid crystals, or organic electronic materials due to its conjugated ketone and nitrile functional groups.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects requiring fluorinated intermediates.

Basic Information

Product Name	5-(2-Fluorophenyl)-5-Oxovaleronitrile
CAS No.	898767-33-4
Molecular Formula	C11H10FNO
Molecular Weight	191.20 g/mol
Synonyms	5-Oxo-5-(2-fluorophenyl)pentanenitrile; 4-Cyano-1-(2-fluorophenyl)butan-1-one; 2-Fluorobenzoylpropionitrile; 1-(2-Fluorophenyl)-4-cyanobutan-1-one; 5-(2-Fluorobenzoyl)valeronitrile; γ-Cyano-2-fluoropropiophenone; 898767-33-4; 5-(2-Fluorophenyl)-5-oxopentanenitrile
EINECS	Contact for details

Quality Control

Every batch of 5-(2-Fluorophenyl)-5-Oxovaleronitrile is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee traceability and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.