Description

4-(2-Fluorophenyl)-4-Oxobutyronitrile is a versatile fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a ketone and a nitrile group adjacent to a fluorinated phenyl ring, makes it a critical precursor for constructing complex heterocycles and pharmacophores. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated drug candidates, including potential kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic materials with specific electronic or optical properties.
• Ligand and Catalyst Development: Employed in the creation of novel chelating ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags or activity-based probes for biochemical research.

Basic Information

Product Name	4-(2-Fluorophenyl)-4-Oxobutyronitrile
CAS No.	898767-30-1
Molecular Formula	C11H8FNO
Molecular Weight	189.18 g/mol
Synonyms	4-Oxo-4-(2-fluorophenyl)butanenitrile; 2-Fluorobenzoylacetonitrile; 3-Oxo-3-(2-fluorophenyl)propanenitrile; 4-(2-Fluorobenzoyl)butyronitrile; 2-Fluorophenyl 3-cyanopropan-1-one; γ-Oxo-2-fluorobenzene butyronitrile; 898767-30-1; 4-(2-Fluorophenyl)-4-oxobutanenitrile
EINECS	Contact for details

Quality Control

Our 4-(2-Fluorophenyl)-4-Oxobutyronitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.