Description

4-(4-Bromo-2-Methylphenyl)-4-Oxobutyric Acid is a high-purity organic building block characterized by its brominated aromatic ketone structure. This compound is a critical intermediate for the synthesis of more complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry and fine chemical manufacturing. The product offers a reliable and consistent starting point for constructing novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or plant growth regulators, leveraging the reactivity of the bromine and ketone functional groups.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialized polymers, such as polyketones or epoxy resins, for high-performance applications.
• Ligand Synthesis: Employed in the preparation of complex organic ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Utilized as a probe or linker molecule in bioconjugation and the development of chemical tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) to fulfill client-specific molecule requests.

Basic Information

Product Name	4-(4-Bromo-2-Methylphenyl)-4-Oxobutyric Acid
CAS No.	898767-28-7
Molecular Formula	C11H11BrO3
Molecular Weight	271.11 g/mol
Synonyms	4-(4-Bromo-2-methylphenyl)-4-oxobutanoic acid; 4-Oxo-4-(4-bromo-2-methylphenyl)butyric acid; γ-Oxo-4-bromo-2-methylbenzenebutanoic acid; 4-(4-Bromo-o-tolyl)-4-oxobutyric acid; Butyric acid, 4-(4-bromo-2-methylphenyl)-4-oxo-; 898767-28-7; 4-(4-Bromo-2-methylphenyl)-4-oxobutanoate
EINECS	Contact for details

Quality Control

Our 4-(4-Bromo-2-Methylphenyl)-4-Oxobutyric Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed when not in use to prevent degradation from atmospheric moisture. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.