Description

4'-Chloro-3'-Fluoro-3-(3-Fluorophenyl)Propiophenone is a high-value fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its precise molecular architecture, featuring strategically placed chlorine and fluorine atoms, makes it a critical building block for the development of complex, bioactive molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogen pattern is leveraged to fine-tune the properties of final products.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials due to its aromatic backbone and halogen substituents.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new fluorination reactions and constructing complex molecular libraries.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized, high-value fine chemicals.

Basic Information

Product Name	4'-Chloro-3'-Fluoro-3-(3-Fluorophenyl)Propiophenone
CAS No.	898767-26-5
Molecular Formula	C15H11ClF2O
Molecular Weight	280.70 g/mol
Synonyms	1-(4-Chloro-3-fluorophenyl)-3-(3-fluorophenyl)-1-propanone; 3-(3-Fluorophenyl)-1-(4-chloro-3-fluorophenyl)propan-1-one; 4'-Chloro-3'-fluoro-3-(3-fluorophenyl)propiophenone; 898767-26-5; Propiophenone, 4'-chloro-3'-fluoro-3-(3-fluorophenyl)-; 1-Propanone, 1-(4-chloro-3-fluorophenyl)-3-(3-fluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 4'-Chloro-3'-Fluoro-3-(3-Fluorophenyl)Propiophenone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.