Description

4'-Bromo-3'-Fluoro-3-(3-Fluorophenyl)Propiophenone is a high-purity, multi-fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of complex, biologically active molecules, particularly within pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogenated motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the bromo-fluoro substitution pattern can influence biological activity and environmental stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for fluorinated organic electronic materials, where halogen atoms fine-tune electronic properties and molecular packing.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create more complex biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes and tags for imaging and diagnostic applications.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for contract research organizations (CROs) serving the life sciences sector.

Basic Information

Product Name	4'-Bromo-3'-Fluoro-3-(3-Fluorophenyl)Propiophenone
CAS No.	898767-23-2
Molecular Formula	C15H11BrF2O
Molecular Weight	325.15 g/mol
Synonyms	1-(4-Bromo-3-fluorophenyl)-3-(3-fluorophenyl)-1-propanone; 3-(3-Fluorophenyl)-1-(4-bromo-3-fluorophenyl)propan-1-one; 4'-Bromo-3'-fluoro-3-(3-fluorophenyl)propiophenone; 898767-23-2; Propiophenone, 4'-bromo-3'-fluoro-3-(3-fluorophenyl)-; 1-Propanone, 1-(4-bromo-3-fluorophenyl)-3-(3-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 4'-Bromo-3'-Fluoro-3-(3-Fluorophenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality supports your R&D and scale-up processes with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.