Description

2',6'-Dimethyl-3-(3-Fluorophenyl)Propiophenone is a high-purity fluorinated aromatic ketone intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a critical building block in the development of complex, biologically active molecules, particularly within pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorinated motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides where the fluorophenyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Employed in the synthesis of advanced polymers and organic electronic materials requiring fluorinated aromatic units.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling.
• Academic & Institutional Research: A valuable reagent for methodological studies in organic chemistry, particularly in cross-coupling and fluorination reactions.

Basic Information

Product Name	2',6'-Dimethyl-3-(3-Fluorophenyl)Propiophenone
CAS No.	898767-14-1
Molecular Formula	C17H17FO
Molecular Weight	256.32 g/mol
Synonyms	3'-Fluoro-2,6-dimethylpropiophenone; 1-(3-Fluorophenyl)-3-(2,6-dimethylphenyl)-1-propanone; 3-(3-Fluorophenyl)-1-(2,6-dimethylphenyl)propan-1-one; 2,6-Dimethyl-3'--fluoropropiophenone; Propiophenone, 2',6'-dimethyl-3-(3-fluorophenyl)-; 898767-14-1; 3-Fluoro-α,2,6-trimethylbenzenepropiophenone
EINECS	Contact for details

Quality Control

Our 2',6'-Dimethyl-3-(3-Fluorophenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.