Description

3-Chloro-1-(2-Fluorophenyl)-1-Oxopropane is a versatile fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and advanced organic electronic materials that require fluorinated aromatic components.
• Chemical Biology Probes: Employed in the creation of fluorinated probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-Chloro-1-(2-Fluorophenyl)-1-Oxopropane
CAS No.	898767-04-9
Molecular Formula	C9H8ClFO
Molecular Weight	186.61 g/mol
Synonyms	2-Fluorophenacyl Chloride; 1-(2-Fluorophenyl)-3-chloropropan-1-one; 3-Chloro-1-(2-fluorophenyl)propan-1-one; ω-Chloro-2'-fluoroacetophenone; 2'-Fluorophenacyl Chloride; 2-Fluorophenyl Chloromethyl Ketone; α-Chloro-2-fluoroacetophenone
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-1-(2-Fluorophenyl)-1-Oxopropane adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.