Description

8-(4-Bromophenyl)-8-Oxooctanenitrile is a versatile and high-purity organic intermediate featuring a bromophenyl ketone moiety linked to a nitrile-terminated alkyl chain. This unique bifunctional structure makes it a critical building block for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for constructing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging the reactivity of both the bromoaryl and nitrile functional groups.
• Liquid Crystal & OLED Material Research: Acts as a building block for creating advanced organic electronic materials due to its rigid aromatic core and flexible aliphatic chain.
• Polymer Modification: Employed to introduce specific functional groups into polymer backbones to alter physical properties like solubility, thermal stability, or adhesion.
• Cross-Coupling Reactions: The bromophenyl group makes it an excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Heck) to create more complex biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.

Basic Information

Product Name	8-(4-Bromophenyl)-8-Oxooctanenitrile
CAS No.	898766-90-0
Molecular Formula	C14H16BrNO
Molecular Weight	294.19 g/mol
Synonyms	8-(4-Bromobenzoyl)octanenitrile; 4'-Bromo-ω-cyanovalerophenone; 8-Oxo-8-(4-bromophenyl)octanenitrile; 1-(4-Bromophenyl)-7-cyano-1-heptanone; 4-Bromophenyl 7-cyanopropyl ketone; ω-Cyano-4'-bromovalerophenone; 8-(p-Bromophenyl)-8-oxooctanenitrile
EINECS	Contact for details

Quality Control

Every batch of 8-(4-Bromophenyl)-8-Oxooctanenitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.