Description

3'-Chloro-2,2-Dimethyl-5'-Fluoropropiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated propiophenone structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents. It is primarily utilized by research institutions and manufacturing facilities in the pharmaceutical and agrochemical sectors seeking reliable, high-quality building blocks for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its halogenated aromatic structure.
• Organic Synthesis Research: Serves as a versatile precursor for academic and industrial research in organic chemistry, enabling the exploration of new chemical entities.
• Material Science: Potential application in the development of specialty polymers and advanced materials requiring specific fluorinated and chlorinated aromatic components.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Detail
Product Name	3'-Chloro-2,2-Dimethyl-5'-Fluoropropiophenone
CAS No.	898766-48-8
Molecular Formula	C11H12ClFO
Molecular Weight	214.66 g/mol
Synonyms	5'-Fluoro-3'-chloro-2,2-dimethylpropiophenone; 1-(3-Chloro-5-fluorophenyl)-2,2-dimethylpropan-1-one; 3-Chloro-5-fluoro-α,α-dimethylpropiophenone; 2,2-Dimethyl-1-(3-chloro-5-fluorophenyl)propan-1-one; Propiophenone, 3'-chloro-2,2-dimethyl-5'-fluoro-; CAS 898766-48-8
EINECS	Contact for details

Quality Control

Our 3'-Chloro-2,2-Dimethyl-5'-Fluoropropiophenone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We are committed to meeting the stringent requirements of cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.