Description

2,2-Dimethyl-3'-Trifluoromethylpropiophenone is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its value lies in the unique combination of a sterically hindered ketone group and a trifluoromethyl substituent, which are critical for modulating the physicochemical properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing lipophilic and metabolically stable trifluoromethyl groups.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorinated moiety can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, leveraging its rigid aromatic structure.
• Organic Synthesis Building Block: Employed in various name reactions and multi-step syntheses to construct complex, fluorinated molecular architectures.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2,2-Dimethyl-3'-Trifluoromethylpropiophenone
CAS No.	898766-39-7
Molecular Formula	C12H13F3O
Molecular Weight	230.23 g/mol
Synonyms	3'-Trifluoromethyl-2,2-dimethylpropiophenone; 1-[3-(Trifluoromethyl)phenyl]-2,2-dimethylpropan-1-one; α,α-Dimethyl-3'-(trifluoromethyl)propiophenone; 2,2-Dimethyl-1-(3-trifluoromethylphenyl)propan-1-one; 3-(Trifluoromethyl)phenyl pivaloyl ketone; Pivaloyl(3-trifluoromethyl)benzene; 898766-39-7 (CAS)
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-3'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.