Description

2,2-Dimethyl-2'-Trifluoromethylpropiophenone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its unique trifluoromethyl-substituted propiophenone structure, which imparts desirable physicochemical properties to target molecules, such as enhanced metabolic stability and lipophilicity. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly those targeting CNS disorders and inflammatory diseases where the trifluoromethyl group is advantageous.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the fluorine atom's ability to improve biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty polymers and liquid crystals with tailored optical and electronic properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecular architectures via reactions like Friedel-Crafts acylation and nucleophilic addition.
• Fluorine Chemistry Studies: An important compound for investigating structure-activity relationships (SAR) and the effects of fluorination in medicinal and materials chemistry.

Basic Information

Product Name	2,2-Dimethyl-2'-Trifluoromethylpropiophenone
CAS No.	898766-36-4
Molecular Formula	C12H13F3O
Molecular Weight	230.23 g/mol
Synonyms	2,2-Dimethyl-1-(2-(trifluoromethyl)phenyl)propan-1-one; 1-(2-(Trifluoromethyl)phenyl)-2,2-dimethylpropan-1-one; α,α-Dimethyl-2'-(trifluoromethyl)propiophenone; 2'-(Trifluoromethyl)-2,2-dimethylpropiophenone; 2,2-Dimethyl-2'-(trifluoromethyl)propiophenone; Propiophenone, 2,2-dimethyl-2'-(trifluoromethyl)-; Trifluoromethyl Dimethyl Propiophenone
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-2'-Trifluoromethylpropiophenone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.