Description

3'-Cyano-2,2-Dimethylpropiophenone is a specialized organic intermediate featuring a cyano-substituted propiophenone core with gem-dimethyl groups. This compound matters as a key building block in the synthesis of complex molecules, offering a unique combination of steric hindrance and reactivity for advanced chemical transformations. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a sterically hindered ketone moiety.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Research: A valuable reagent for method development in organic synthesis, including studies on cyano group transformations and C-C bond formation.

Basic Information

Product Name	3'-Cyano-2,2-Dimethylpropiophenone
CAS No.	898766-12-6
Molecular Formula	C12H13NO
Molecular Weight	187.24 g/mol
Synonyms	2,2-Dimethyl-3'-cyanopropiophenone; 3-Cyano-2,2-dimethylpropiophenone; Propiophenone, 3'-cyano-2,2-dimethyl-; 1-(3-Cyanophenyl)-2,2-dimethylpropan-1-one; 2,2-Dimethyl-1-(3-cyanophenyl)propan-1-one; α,α-Dimethyl-m-cyanopropiophenone; m-Cyano-α,α-dimethylpropiophenone
EINECS	Contact for details

Quality Control

Our 3'-Cyano-2,2-Dimethylpropiophenone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP-aligned environments and research requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.