Description

2,2-Dimethyl-3',4',5'-Trifluorobutyrophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in its unique trifluoromethyl-substituted aromatic structure, which is crucial for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the development of fluorinated liquid crystals for high-performance display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed as a building block for electron-transport materials and host materials in OLED devices.
• Advanced Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers with enhanced thermal and chemical resistance.
• Chemical Research & Development: A versatile reagent for exploring novel fluorination reactions and constructing complex molecular architectures in academic and industrial labs.

Basic Information

Product Name	2,2-Dimethyl-3',4',5'-Trifluorobutyrophenone
CAS No.	898766-08-0
Molecular Formula	C12H13F3O
Molecular Weight	230.23 g/mol
Synonyms	3',4',5'-Trifluoro-2,2-dimethylbutyrophenone; 1-(3,4,5-Trifluorophenyl)-2,2-dimethylpropan-1-one; 2,2-Dimethyl-1-(3,4,5-trifluorophenyl)propan-1-one; Butyrophenone, 2,2-dimethyl-3',4',5'-trifluoro-; α,α-Dimethyl-3,4,5-trifluorophenylacetone; TFBP Derivative; Trifluorinated Butyrophenone Intermediate
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-3',4',5'-Trifluorobutyrophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.