Description

2'-Chloro-2,2-Dimethyl-4'-Fluorobutyrophenone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, makes it a valuable precursor for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, Grignard reactions, and other transformations to introduce functionalized aromatic groups.
• Chemical Research & Development: A valuable compound for academic and industrial R&D exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	2'-Chloro-2,2-Dimethyl-4'-Fluorobutyrophenone
CAS No.	898765-86-1
Molecular Formula	C12H14ClFO
Molecular Weight	228.69 g/mol
Synonyms	4'-Fluoro-2'-chloro-2,2-dimethylbutyrophenone; 1-(4-Fluoro-2-chlorophenyl)-3,3-dimethylbutan-1-one; 3,3-Dimethyl-1-(4-fluoro-2-chlorophenyl)-1-butanone; 2,2-Dimethyl-1-(4-fluoro-2-chlorophenyl)butan-1-one; α,α-Dimethyl-4-fluoro-2-chlorohydrocinnamophenone; Butyrophenone, 2'-chloro-2,2-dimethyl-4'-fluoro-; 898765-86-1
EINECS	Contact for details

Quality Control

Our 2'-Chloro-2,2-Dimethyl-4'-Fluorobutyrophenone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.