Description

2,2-Dimethyl-3'-Trifluoromethylbutyrophenone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group and a hindered carbonyl, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group can improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials, contributing to the tuning of electronic properties and stability.
• Advanced Polymer Chemistry: Employed as a monomer or modifier in the synthesis of specialty polymers with specific thermal, chemical, or surface properties.
• Organic Synthesis & Methodology Development: A valuable substrate for academic and industrial research into new fluorination reactions, carbonyl chemistry, and asymmetric synthesis.

Basic Information

Product Name	2,2-Dimethyl-3'-Trifluoromethylbutyrophenone
CAS No.	898765-80-5
Molecular Formula	C13H15F3O
Molecular Weight	244.26 g/mol
Synonyms	3'-Trifluoromethyl-2,2-dimethylbutyrophenone; 1-[3-(Trifluoromethyl)phenyl]-2,2-dimethyl-1-propanone; α,α-Dimethyl-3'-(trifluoromethyl)butyrophenone; 2,2-Dimethyl-1-(3-trifluoromethylphenyl)propan-1-one; Butyrophenone, 2,2-dimethyl-3'-trifluoromethyl-; 3-(Trifluoromethyl)phenyl pivalyl ketone; Pivaloyl-3-trifluoromethylbenzene
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-3'-Trifluoromethylbutyrophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.