Description

4'-Bromo-2,2-dimethyl-3'-fluorobutyrophenone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct halogenated aromatic ketone structure. This compound is of significant value in modern synthetic organic chemistry, particularly for constructing complex molecular frameworks. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals due to its rigid aromatic core and functional groups.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a substrate for further functionalization in academic and industrial R&D laboratories.
• Chemical Reference Standard: Utilized as an analytical standard for quality control and method development in analytical chemistry.

Basic Information

Product Name	4'-Bromo-2,2-dimethyl-3'-fluorobutyrophenone
CAS No.	898765-68-9
Molecular Formula	C12H14BrFO
Molecular Weight	273.14 g/mol
Synonyms	1-(4-Bromo-3-fluorophenyl)-2,2-dimethylbutan-1-one; 3'-Fluoro-4'-bromo-2,2-dimethylbutyrophenone; 4'-Bromo-3'-fluoro-2,2-dimethylbutyrophenone; α,α-Dimethyl-4-bromo-3-fluorobutyrophenone; Butan-1-one, 1-(4-bromo-3-fluorophenyl)-2,2-dimethyl-; 898765-68-9 (CAS)
EINECS	Contact for details

Quality Control

Our 4'-Bromo-2,2-dimethyl-3'-fluorobutyrophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.