Description

2,2,3',5'-Tetramethylbutyrophenone is a specialized organic compound belonging to the butyrophenone class, characterized by its unique tetramethyl substitution pattern. This structural feature makes it a valuable intermediate and building block in advanced organic synthesis, particularly for creating complex molecules with specific steric and electronic properties. It is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries who require high-purity, structurally defined intermediates for their synthetic pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring sterically hindered ketone functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where its specific substitution pattern can influence biological activity.
• Material Science Research: Serves as a monomer or precursor in the development of novel polymers and advanced organic materials.
• Organic Synthesis Reagent: Employed in academic and industrial R&D laboratories for constructing complex molecular architectures, including natural product analogs.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Utilized in the manufacture of dyes, flavors, and fragrances that require specific alkylated aromatic ketone structures.

Basic Information

Product Name	2,2,3',5'-Tetramethylbutyrophenone
CAS No.	898765-66-7
Molecular Formula	C14H20O
Molecular Weight	204.31 g/mol
Synonyms	2,2,3',5'-Tetramethylbutyrophenone; 1-(2,6-Dimethylphenyl)-3,3-dimethylbutan-1-one; 3,3-Dimethyl-1-(2,6-xylyl)-1-butanone; Butanone, 3,3-dimethyl-1-(2,6-dimethylphenyl)-; Tetramethylbutyrophenone; TMButyrophenone
EINECS	Contact for details

Quality Control

Our 2,2,3',5'-Tetramethylbutyrophenone is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in research and scale-up synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.