Description

2',2,2,5'-Tetramethylbutyrophenone is a specialized organic compound belonging to the class of substituted butyrophenones, serving as a valuable intermediate in advanced chemical synthesis. Its unique tetramethyl-substituted structure provides steric and electronic properties that are critical for developing high-performance materials and fine chemicals. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to innovate and optimize synthetic pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds requiring a sterically hindered ketone functionality.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structure can contribute to improved efficacy and environmental profile.
• Photoinitiator Precursor: Serves as a precursor in the manufacture of photoinitiators for UV-curable inks, coatings, and adhesives.
• Ligand and Catalyst Development: Employed in organic and organometallic chemistry for the development of novel ligands and catalysts used in asymmetric synthesis.
• Material Science Research: Acts as a monomer or modifier in the research of specialty polymers and high-performance resins.
• Flavor & Fragrance Intermediate: Utilized in the synthesis of complex aroma chemicals that benefit from its specific molecular framework.

Basic Information

Product Name	2',2,2,5'-Tetramethylbutyrophenone
CAS No.	898765-58-7
Molecular Formula	C14H20O
Molecular Weight	204.31 g/mol
Synonyms	2,2,5,5-Tetramethylbutyrophenone; 1-(2,5-Dimethylphenyl)-3,3-dimethylbutan-1-one; α,α,2,5-Tetramethylbutyrophenone; 3,3-Dimethyl-1-(2,5-dimethylphenyl)butan-1-one; Butyrophenone, 2',2,2,5'-tetramethyl-; TMButyrophenone; Tetramethyl Butyrophenone
EINECS	Contact for details

Quality Control

Our 2',2,2,5'-Tetramethylbutyrophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by GC/HPLC, and control of key impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.