Description

3'-Bromo-2,2-dimethylbutyrophenone is a specialized brominated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular structure, which serves as a versatile precursor for constructing complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and plant growth regulators with tailored properties.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed as a monomer or functionalization agent in the synthesis of polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Scale-up: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	3'-Bromo-2,2-dimethylbutyrophenone
CAS No.	898765-34-9
Molecular Formula	C12H15BrO
Molecular Weight	255.15 g/mol
Synonyms	1-(3-Bromophenyl)-2,2-dimethyl-1-propanone; 3-Bromo-α,α-dimethylhydrocinnamophenone; 2,2-Dimethyl-1-(3-bromophenyl)propan-1-one; 3'-Bromo-α,α-dimethylhydrocinnamophenone; 1-Propanone, 1-(3-bromophenyl)-2,2-dimethyl-; Butyrophenone, 3'-bromo-2,2-dimethyl-; (3-Bromophenyl)(tert-butyl)methanone
EINECS	Contact for details

Quality Control

Our 3'-Bromo-2,2-dimethylbutyrophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.