Description

3',5'-Difluoro-3,3-Dimethylbutyrophenone is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both a reactive ketone group and strategically placed fluorine atoms, enabling precise modifications to enhance the properties of target molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the fluorine atoms can improve biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced polymers and liquid crystals, where fluorinated aromatic units impart desirable thermal and chemical resistance properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3',5'-Difluoro-3,3-Dimethylbutyrophenone
CAS No.	898764-98-2
Molecular Formula	C12H14F2O
Molecular Weight	212.24 g/mol
Synonyms	1-(3,5-Difluorophenyl)-3,3-dimethylbutan-1-one; 3,3-Dimethyl-1-(3,5-difluorophenyl)butan-1-one; 3,5-Difluoro-3,3-dimethylbutyrophenone; Butan-1-one, 1-(3,5-difluorophenyl)-3,3-dimethyl-; 3',5'-Difluoro-α,α-dimethylbutyrophenone
EINECS	Contact for details

Quality Control

Our 3',5'-Difluoro-3,3-Dimethylbutyrophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.