Description

3,3-Dimethyl-2'-Fluorobutyrophenone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a fluorinated aromatic ring and a sterically hindered ketone side chain, makes it a valuable precursor for the development of complex molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries. It serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals requiring specific fluorinated motifs.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic systems to modulate bioavailability, metabolic stability, and receptor binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the introduction of fluorine atoms can enhance biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced organic materials with tailored optical or electronic properties.
• Ligand and Catalyst Development: Employed in the preparation of complex organic ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Fluorine Chemistry Studies: A valuable substrate for academic and industrial research exploring new fluorination methodologies and the unique reactivity of fluorinated compounds.

Basic Information

Product Name	3,3-Dimethyl-2'-Fluorobutyrophenone
CAS No.	898764-70-0
Molecular Formula	C12H15FO
Molecular Weight	194.25 g/mol
Synonyms	2'-Fluoro-3,3-dimethylbutyrophenone; 1-(2-Fluorophenyl)-3,3-dimethylbutan-1-one; 3,3-Dimethyl-1-(2-fluorophenyl)butan-1-one; Butan-1-one, 1-(2-fluorophenyl)-3,3-dimethyl-; α,α-Dimethyl-2-fluorohydrocinnamone; 2-Fluoro-α,α-dimethylhydrocinnamaldehyde (related aldehyde); Fluorinated dimethylbutyrophenone derivative
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure the consistency and purity of our chemical intermediates. Every batch of 3,3-Dimethyl-2'-Fluorobutyrophenone is analyzed using advanced techniques such as HPLC, GC, NMR, and mass spectrometry to verify identity and purity against stringent internal specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. Our commitment to quality supports compliance with the standards required for research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.