Description

4'-Bromo-2'-Fluoro-3-Phenylpropiophenone is a high-purity, advanced pharmaceutical intermediate with a distinct halogenated aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific bromo and fluoro substituents into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of halogen substitution on bioactivity and metabolic stability.
• Agrochemical Synthesis: Serves as a precursor in the development of new-generation herbicides and fungicides with enhanced efficacy.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring specific aromatic ketone frameworks.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) engaged in organic synthesis and method development projects.

Basic Information

Product Name	4'-Bromo-2'-Fluoro-3-Phenylpropiophenone
CAS No.	898764-54-0
Molecular Formula	C15H12BrFO
Molecular Weight	307.16 g/mol
Synonyms	1-(4-Bromo-2-fluorophenyl)-3-phenylpropan-1-one; 3-Phenyl-1-(4-bromo-2-fluorophenyl)propan-1-one; 4'-Bromo-2'-fluorodihydrochalcone; 898764-54-0; 4-Bromo-2-fluoro-3-phenylpropiophenone; Propiophenone, 4'-bromo-2'-fluoro-3-phenyl-
EINECS	Contact for details

Quality Control

Our 4'-Bromo-2'-Fluoro-3-Phenylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.