Description

3'-Chloro-4'-Fluoro-3-Phenylpropiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct halogenated aromatic structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs.
• API Synthesis: Serves as a crucial precursor in multi-step synthetic routes for active pharmaceutical ingredients, leveraging its reactive ketone and halogen functionalities.
• Chemical Research: Used in academic and industrial laboratories for studying structure-activity relationships (SAR) and developing novel synthetic methodologies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals where a halogenated propiophenone scaffold is required.
• Material Science Research: Potential use as a monomer or building block for synthesizing specialized polymers or organic electronic materials.

Basic Information

Product Name	3'-Chloro-4'-Fluoro-3-Phenylpropiophenone
CAS No.	898764-42-6
Molecular Formula	C15H12ClFO
Molecular Weight	262.71 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)-3-phenylpropan-1-one; 3-Phenyl-1-(3-chloro-4-fluorophenyl)propan-1-one; 3'-Chloro-4'-fluoro-3-phenylpropiophenone; 3-Chloro-4-fluoro-3-phenylpropiophenone; 898764-42-6; Propiophenone, 3'-chloro-4'-fluoro-3-phenyl-
EINECS	Contact for details

Quality Control

Our 3'-Chloro-4'-Fluoro-3-Phenylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.