Description

4'-Chloro-3'-Fluoro-3-Phenylpropiophenone is a high-purity fluorinated and chlorinated aromatic ketone building block of significant synthetic utility. This compound matters as a critical intermediate in modern organic synthesis, enabling the construction of complex molecules for advanced material and life science applications. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides with improved efficacy and environmental profiles.
• Material Science Precursor: Serves as a building block for liquid crystals and advanced polymers requiring specific halogenated aromatic structures.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and as a substrate for exploring new fluorination methodologies.
• Academic & R&D: A valuable reagent for university and corporate research laboratories focused on medicinal chemistry and synthetic methodology.

Basic Information

Product Name	4'-Chloro-3'-Fluoro-3-Phenylpropiophenone
CAS No.	898764-39-1
Molecular Formula	C15H12ClFO
Molecular Weight	262.71 g/mol
Synonyms	1-(4-Chloro-3-fluorophenyl)-3-phenylpropan-1-one; 3-Phenyl-1-(4-chloro-3-fluorophenyl)propan-1-one; 4-Chloro-3-fluoro-3-phenylpropiophenone; 898764-39-1; 4'-Chloro-3'-fluorodihydrochalcone; 3-Phenylpropyl 4-chloro-3-fluorophenyl ketone
EINECS	Contact for details

Quality Control

Our 4'-Chloro-3'-Fluoro-3-Phenylpropiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our commitment to quality supports your R&D and scale-up processes with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.