Description

4-Bromo-3-Fluoro-4'-(3-Pyrrolinomethyl) Benzophenone is a high-purity, multi-functional benzophenone derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and research chemical, enabling the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated and nitrogen-containing motifs into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its benzophenone core and pyrrolinomethyl functionality.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the halogen and nitrogen groups can contribute to biological activity and binding affinity.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, liquid crystals, and photoactive materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a scaffold for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Chemical Biology Probe: Useful for creating photoaffinity labels or molecular probes to study protein-ligand interactions and enzyme mechanisms.

Basic Information

Product Name	4-Bromo-3-Fluoro-4'-(3-Pyrrolinomethyl) Benzophenone
CAS No.	898764-28-8
Molecular Formula	C18H16BrFNO
Molecular Weight	361.23 g/mol
Synonyms	4-Bromo-3-fluoro-4'-(pyrrolidin-1-ylmethyl)benzophenone; (4-Bromo-3-fluorophenyl)[4-(pyrrolidin-1-ylmethyl)phenyl]methanone; 1-({4-[(4-Bromo-3-fluorophenyl)carbonyl]phenyl}methyl)pyrrolidine; Benzophenone, 4-bromo-3-fluoro-4'-(3-pyrrolinomethyl)-; 898764-28-8
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-3-Fluoro-4'-(3-Pyrrolinomethyl) Benzophenone adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality management systems and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.