Description

4-Chloro-2-Fluoro-2'-(3-Pyrrolinomethyl) Benzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its complex benzophenone core structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Organic Synthesis Reagent: Used in complex multi-step organic reactions, including cross-coupling and functional group transformations.
• Chemical Research & Development: Serves as a precursor for developing new chemical libraries and for structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the final stages or penultimate steps of API synthesis for specialized medications.
• Contract Research & Manufacturing (CRAM): Supplied to CRAM organizations supporting global pharmaceutical pipelines.
• Academic Research: Used in university and institutional labs for advanced organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	4-Chloro-2-Fluoro-2'-(3-Pyrrolinomethyl) Benzophenone
CAS No.	898763-68-3
Molecular Formula	C18H16ClFNO
Molecular Weight	316.78 g/mol
Synonyms	4-Chloro-2-fluoro-2'-(3-pyrrolidinylmethyl)benzophenone; 2-(4-Chloro-2-fluorobenzoyl)-N-(pyrrolidin-3-ylmethyl)benzamide (tautomeric form); 898763-68-3; Benzophenone, 4-chloro-2-fluoro-2'-(3-pyrrolidinylmethyl)-; 4-Chloro-2-fluoro-2'-(pyrrolidin-3-ylmethyl)benzophenone; 2'-[(3-Pyrrolidinyl)methyl]-4-chloro-2-fluorobenzophenone
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoro-2'-(3-Pyrrolinomethyl) Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.