Description

3-Thiomorpholinomethyl-4'-Trifluoromethylbenzophenone is a high-value, multifunctional chemical building block characterized by its benzophenone core substituted with a thiomorpholine and a trifluoromethyl group. This unique structure makes it a critical intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and agrochemicals where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily sought after by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers with specific optical or electronic properties.
• Ligand and Catalyst Development: The thiomorpholine moiety can act as a coordinating group in the design of novel ligands for catalysis or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the creation of photoaffinity labels or other molecular probes for studying biological systems and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific scaffold.

Basic Information

Product Name	3-Thiomorpholinomethyl-4'-Trifluoromethylbenzophenone
CAS No.	898763-49-0
Molecular Formula	C19H18F3NO2S
Molecular Weight	381.41 g/mol
Synonyms	4'-(Trifluoromethyl)-3-(thiomorpholinomethyl)benzophenone; 3-[(Thiomorpholin-4-yl)methyl]-4'-(trifluoromethyl)benzophenone; Benzophenone, 3-[(thiomorpholin-4-yl)methyl]-4'-(trifluoromethyl)-; 898763-49-0; 3-Thiomorpholin-4-ylmethyl-4'-trifluoromethylbenzophenone
EINECS	Contact for details

Quality Control

Our 3-Thiomorpholinomethyl-4'-Trifluoromethylbenzophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles by HPLC, NMR, and other relevant methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.