Description

4'-(4-Methylpiperazinomethyl)-3,4,5-Trifluorobenzophenone is a high-value trifluorinated benzophenone derivative, serving as a critical advanced pharmaceutical intermediate. Its core value lies in enabling the synthesis of complex active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and agrochemical industries, particularly those focused on novel drug discovery and process optimization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group contributes to biological activity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex organic molecules in pilot plant and commercial manufacturing.
• Material Science Precursor: Potential use in the development of specialty polymers and advanced organic materials requiring fluorinated aromatic components.

Basic Information

Product Name	4'-(4-Methylpiperazinomethyl)-3,4,5-Trifluorobenzophenone
CAS No.	898763-42-3
Molecular Formula	C20H20F3N2O
Molecular Weight	361.38 g/mol
Synonyms	3,4,5-Trifluoro-4'-(4-methyl-1-piperazinylmethyl)benzophenone; 1-[[(3,4,5-Trifluorophenyl)[4-(4-methyl-1-piperazinyl)phenyl]methylidene]methyl]-4-methylpiperazine; 4'-(4-Methylpiperazin-1-ylmethyl)-3,4,5-trifluorobenzophenone; 3,4,5-Trifluoro-4'-(N-methylpiperazinomethyl)benzophenone; Benzophenone, 4'-(4-methyl-1-piperazinylmethyl)-3,4,5-trifluoro-; 898763-42-3; 4-(4-Methylpiperazinomethyl)-3,4,5-trifluorobenzophenone
EINECS	Contact for details

Quality Control

Our 4'-(4-Methylpiperazinomethyl)-3,4,5-Trifluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.