Description

2'-(4-Methylpiperazinomethyl)-3,4,5-Trifluorobenzophenone is a high-value trifluorinated benzophenone derivative, serving as a critical advanced pharmaceutical intermediate. Its molecular structure, featuring a piperazine moiety and fluorine atoms, is engineered to enhance the metabolic stability and bioavailability of target drug candidates. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for CNS-targeted drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its trifluoromethyl and piperazine functional groups.
• Protease Inhibitor Development: Serves as a precursor in the synthesis of compounds targeting specific protease enzymes.
• Kinase Inhibitor Synthesis: Employed in the research and development of potential kinase inhibitor candidates for oncology applications.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes for clients.

Basic Information

Item	Detail
Product Name	2'-(4-Methylpiperazinomethyl)-3,4,5-Trifluorobenzophenone
CAS No.	898762-54-4
Molecular Formula	C19H18F3N2O
Molecular Weight	356.36 g/mol
Synonyms	3,4,5-Trifluoro-2-[(4-methyl-1-piperazinyl)methyl]benzophenone; 2-[(4-Methylpiperazin-1-yl)methyl]-3,4,5-trifluorobenzophenone; 3,4,5-Trifluoro-2-((4-methylpiperazin-1-yl)methyl)benzophenone; 898762-54-4; Benzophenone, 3,4,5-trifluoro-2-[(4-methyl-1-piperazinyl)methyl]-; 2'-(4-Methyl-1-piperazinylmethyl)-3,4,5-trifluorobenzophenone
EINECS	Contact for details

Quality Control

Our 2'-(4-Methylpiperazinomethyl)-3,4,5-Trifluorobenzophenone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and stringent impurity profiling ensures the material meets the exacting standards required for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.